Person

Dr., Universitätsprofessor

Twan Lammers

Twan Lammers Copyright: © Private
Lehrstuhl für Experimentelle Molekulare Bildgebung

Address

Building: CBMS

Room: 104

Forckenbeckstr. 55

52074 Aachen

Contact

WorkPhone
Phone: +49 241 80 85907
 

Twan Lammers obtained a D.Sc. in Radiation Oncology from Heidelberg University in 2008 and a Ph.D. in Pharmaceutics from Utrecht University in 2009. In the same year, he started the Nanomedicine and Theranostics group at the Institute for Experimental Molecular Imaging (ExMI) at RWTH Aachen University Clinic. In 2014, he was promoted to full professor of medicine. His group aims to individualize and improve disease treatment by combining drug targeting with imaging. To this end, image-guided (theranostic) drug delivery systems are being developed, as well as materials and methods to monitor tumor growth, angiogenesis, inflammation, fibrosis and metastasis. He has published over 250 papers, and received multiple scholarships and awards, including a starting and consolidator grant from the European Research Council, the Young Investigator Award of the Controlled Release Society (2015), the Adritelf International Award (2015) and the Belgian Society for Pharmaceutical Science International Award (2020). He is on the editorial board of 10 journals, and serves as a handling editor for the Journal of Controlled Release, Drug Delivery and Translational Research, and Molecular Imaging and Biology. Since 2019, he is included in the Clarivate Analytics list of Highly Cited Researchers.

Selected publications:

  1. Sun Q, Baues M, Klinkhammer B, Ehling J, Djudjaj S, Drude N, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank D, Botnar R, Kiessling F, Floege J, Lammers T*, Boor P*. Elastin imaging enables non-invasive staging and treatment monitoring of kidney fibrosis. Science Translational Medicine 11, eaat4865 (2019)

  2. Van der Meel R, Sulheim E, Shi Y, Kiessling F, Mulder W, Lammers T. Smart cancer nanomedicine. Nature Nanotechnology 14, 1007-1017 (2019)

  3. Lammers T*, Sofias A, Meel R, Schiffelers R, Storm G, Tacke F, Koschmieder S, Brümmendorf T, Kiessling F, Metselaar J*. Dexamethasone nanomedicines for COVID-19. Nature Nanotechnology 15, 622-624 (2020)

  4. May J, Golombek S, Baues M, Dasgupta A, Drude N, Rix A, Rommel D, Stilfried S, Appold L, Pola R, Pechar M, Bloois L, Storm G, Kuehne A, Gremse F, Theek B, Kiessling F, Lammers T. Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation. Theranostics 10, 1948-1959 (2020)

  5. Wang B, Van Herck S, Chen Y, Bai X, Zhong Z, De Swarte K, Lambrecht B, Sanders N, Lienenklaus S, Scheeren H, David S, Kiessling F, Lammers T*, De Geest B*, Shi Y*. Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles. Journal of the American Chemical Society 142, 12133-12139 (2020)

 

Publications

Title Author(s)
[Journal Article]
Cyclic Arginine–Glycine–Aspartate‐Decorated Lipid Nanoparticle Targeting toward Inflammatory Lesions Involves Hitchhiking with Phagocytes
In: Advanced science, 8 (13), 2100370, 2021
[DOI: 10.1002/advs.202100370]
Sofias, Alexandros Marios (Corresponding author)
Bjørkøy, Geir
Ochando, Jordi
Sønstevold, Linda
Hegvik, Maria
Davies, Catharina de Lange
Haraldseth, Olav
Lammers, Twan
Mulder, Willem J. M.
Hak, Sjoerd (Corresponding author)
[Journal Article]
? electron-stabilized polymeric micelles potentiate docetaxel therapy in advanced-stage gastrointestinal cancer
In: Biomaterials: biomaterials reviews online, 266, 120432, 2021
[DOI: 10.1016/j.biomaterials.2020.120432]
Liang, Chenghua
Bai, Xiangyang
Qi, Cuiling
Sun, Qingxue
Han, Xiaoyan
Lan, Tianyun
Zhang, Haibo
Zheng, Xiaoming
Liang, Rongpu
Jiao, Ju
Zheng, Zongheng
Fang, Jiafeng
Lei, Purun
Wang, Yan
Möckel, Diana
Metselaar, Josbert M.
Storm, Gert
Hennink, Wim E.
Kiessling, Fabian
Wei, Hongbo
Lammers, Twan
Shi, Yang
Wei, Bo
[Journal Article]
Roadmap on nanomedicine
In: Nanotechnology, 32 (1), 012001, 2021
[DOI: 10.1088/1361-6528/abaadb]
Decuzzi, Paolo
Peer, Dan
Di Mascolo, Daniele
Palange, Anna Lisa
Manghnani, Purnima Naresh
Moghimi, S. Moein
Farhangrazi, Z. Shadi
Howard, Kenneth A.
Rosenblum, Daniel
Liang, Tingxizi
Chen, Zhaowei
Wang, Zejun
Zhu, Jun-Jie
Gu, Zhen
Korin, Netanel
Letourneur, Didier
Chauvierre, Cédric
van der Meel, Roy
Kiessling, Fabian
Lammers, Twan
[Journal Article]
A collagen-binding protein enables molecular imaging of kidney fibrosis in vivo
In: Kidney international, 97 (3), 609-614, 2020
[DOI: 10.1016/j.kint.2019.08.029]
Baues, Maike
Klinkhammer, Barbara M.
Ehling, Josef
Gremse, Felix
van Zandvoort, Marc A. M. J.
Reutelingsperger, Chris P. M.
Daniel, Christoph
Amann, Kerstin
Bábí?ková, Janka
Kiessling, Fabian
Floege, Jürgen
Lammers, Twan
Boor, Peter
[Journal Article]
Systematic evaluation of design features enables efficient selection of ? electron-stabilized polymeric micelles
In: International journal of pharmaceutics, 584, 119409, 2020
[DOI: 10.1016/j.ijpharm.2020.119409]
Sheybanifard, Maryam
Beztsinna, Nataliia
Bagheri, Mahsa
Buhl, Eva Miriam
Bresseleers, Jaleesa
Varela-Moreira, Aida
Shi, Yang
van Nostrum, Cornelus F.
van der Pluijm, Gabri
Storm, Gert
Hennink, Wim E.
Lammers, Twan
Metselaar, Josbert M.
[Journal Article]
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism
In: Circulation research, 126 (8), e37-e52, 2020
[DOI: 10.1161/CIRCRESAHA.119.315625]
Shi, Chongxu
Kim, Tehyung
Steiger, Stefanie
Mulay, Shrikant R.
Klinkhammer, Barbara M.
Bäuerle, Tobias
Melica, Maria Elena
Romagnani, Paola
Möckel, Diana
Baues, Maike
Yang, Luying
Brouns, Sanne L N.
Heemskerk, Johan W M.
Braun, Attila
Lammers, Twan
Boor, Peter
Anders, Hans-Joachim
[Contribution to a book, Journal Article]
Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles
In: Journal of controlled release, 328, 805-816, 2020
[DOI: 10.1016/j.jconrel.2020.09.046]
Biancacci, Ilaria
Sun, Qingxue
Möckel, Diana
Gremse, Felix
Rosenhain, Stefanie
Kiessling, Fabian
Bartneck, Matthias
Hu, Qizhi
Thewissen, Marielle
Storm, Gert
Hennink, Wim E.
Shi, Yang
Rijcken, Cristianne J. F.
Lammers, Twan
Sofias, Alexandros Marios
[Journal Article]
Tuning Optical Properties of BODIPY Dyes by Pyrrole Conjugation for Photoacoustic Imaging
In: Advanced optical materials, 8 (11), 1902115, 2020
[DOI: 10.1002/adom.201902115]
Merkes, Jean Michél
Lammers, Twan
Kancherla, R.
Rüping, Magnus
Kiessling, Fabian
Banala, Srinivas (Corresponding author)
[Journal Article]
Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance
In: Journal of nanobiotechnology, 18, 22, 2020
[DOI: 10.1186/s12951-020-0580-1]
Dadfar, Seyed Mohammadali
Camozzi, Denise
Darguzyte, Milita
Roemhild, Karolin
Varvarà, Paola
Metselaar, Josbert M.
Banala, Srinivas
Straub, Marcel
Güvener, Nihan
Engelmann, Ulrich
Slabu, Ioana
Buhl, Miriam
van Leusen, Jan
Kögerler, Paul
Hermanns-Sachweh, Benita
Schulz, Volkmar
Kiessling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Optimizing the Geometry of Photoacoustically Active Gold Nanoparticles for Biomedical Imaging
In: ACS photonics, 7 (3), 646-652, 2020
[DOI: 10.1021/acsphotonics.9b01418]
Garcia-Álvarez, Rafaela
Chen, Lisa
Nedilko, Alexander
Sánchez-Iglesias, Ana
Rix, Anne
Lederle, Wiltrud
Pathak, Vertika
Lammers, Twan
Von Plessen, Geero
Kostarelos, Kostas
Liz-Marzan, Luis M.
Kuehne, Alexander J. C. (Corresponding author)
Chigrin, Dmitry N. (Corresponding author)
[Journal Article]
Dexamethasone nanomedicines for COVID-19
In: Nature nanotechnology, 15 (8), 622-624, 2020
[DOI: 10.1038/s41565-020-0752-z]
Lammers, Twan
Sofias, Alexandros Marios
van der Meel, Roy
Schiffelers, Raymond
Storm, Gert
Tacke, Frank
Koschmieder, Steffen
Brümmendorf, Tim H.
Kiessling, Fabian
Metselaar, Josbert M.
[Journal Article]
The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy
In: Theranostics, 10 (17), 7921-7924, 2020
[DOI: 10.7150/thno.49577]
Shi, Yang
van der Meel, Roy
Chen, Xiaoyuan
Lammers, Twan
[Journal Article]
Drug Loading in Poly(butyl cyanoacrylate)-Based Polymeric Microbubbles
In: Molecular pharmaceutics, 17 (8), 2840-2848, 2020
[DOI: 10.1021/acs.molpharmaceut.0c00242]
Liu, Mengjiao
Dasgupta, Anshuman
Koczera, Patrick
Schipper, Sandra
Rommel, Dirk
Shi, Yang
Kiessling, Fabian
Lammers, Twan
[Journal Article]
Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation
In: Theranostics, 10 (4), 1948-1959, 2020
[DOI: 10.7150/thno.41161]
May, Jan-Niklas
Golombek, Susanne K.
Baues, Maike
Dasgupta, Anshuman
Drude, Natascha
Rix, Anne
Rommel, Dirk
von Stillfried, Saskia
Appold, Lia
Pola, Robert
Pechar, Michal
van Bloois, Louis
Storm, Gert
Kuehne, Alexander J. C.
Gremse, Felix
Theek, Benjamin
Kiessling, Fabian
Lammers, Twan
[Journal Article]
Just dose it
In: Nature materials, 19 (12), 1257-1258, 2020
[DOI: 10.1038/s41563-020-00855-7]
Lammers, Twan
[Journal Article]
The success of nanomedicine
In: Nano today, 31, 100853, 2020
[DOI: 10.1016/j.nantod.2020.100853]
Lammers, T.
Ferrari, M.
[Journal Article]
Cancer nanomedicine meets immunotherapy: opportunities and challenges
In: Acta pharmacologica Sinica : APS, 41, 954-958, 2020
[DOI: 10.1038/s41401-020-0448-9]
Sun, Qingxue
Bai, Xiangyang
Sofias, Alexandros Marios
van der Meel, Roy
Ruiz-Hernandez, Eduardo
Storm, Gert
Hennink, Wim E.
De Geest, Bruno G.
Kiessling, Fabian
Yu, Hai-Jun
Lammers, Twan (Corresponding author)
Shi, Yang (Corresponding author)
[Journal Article]
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
In: Journal of the American Chemical Society, 142 (28), 12133-12139, 2020
[DOI: 10.1021/jacs.0c01928]
Wang, Bi
Van Herck, Simon
Chen, Yong
Bai, Xiangyang
Zhong, Zifu
Deswarte, Kim
Lambrecht, Bart N.
Sanders, Niek N.
Lienenklaus, Stefan
Scheeren, Hans W.
David, Sunil A.
Kiessling, Fabian
Lammers, Twan (Corresponding author)
De Geest, Bruno G.
Shi, Yang (Corresponding author)
[Contribution to a book, Journal Article]
A Doxorubicin-Glucuronide Prodrug Released from Nanogels Activated by High-Intensity Focused Ultrasound Liberated β-Glucuronidase
In: Pharmaceutics / Molecular Diversity Preservation International, 12 (6), 536, 2020
[DOI: 10.3390/pharmaceutics12060536]
Besse, Helena C.
Chen, Yinan
Scheeren, Hans W.
Metselaar, Josbert M.
Lammers, Twan
Moonen, Chrit T. W.
Hennink, Wim E.
Deckers, Roel (Corresponding author)
[Journal Article]
Influence of Riboflavin Targeting on Tumor Accumulation and Internalization of Peptostar Based Drug Delivery Systems
In: Bioconjugate chemistry, 31 (12), 2691-2696, 2020
[DOI: 10.1021/acs.bioconjchem.0c00593]
Darguzyte, Milita
Holm, Regina
Baier, Jasmin
Drude, Natascha Ingrid
Schultze, Jennifer
Koynov, Kaloian
Schwiertz, David
Dadfar, Seyed Mohammadali
Lammers, Twan
Barz, Matthias
Kiessling, Fabian (Corresponding author)
[Contribution to a book, Journal Article]
Riboflavin-Targeted Drug Delivery
In: Cancers, 12 (2), 295, 2020
[DOI: 10.3390/cancers12020295]
Darguzyte, Milita
Drude, Natascha
Lammers, Twan
Kiessling, Fabian (Corresponding author)
[Journal Article]
Challenges in nanomedicine clinical translation
In: Drug Delivery and Translational Research, 10, 721-725, 2020
[DOI: 10.1007/s13346-020-00740-5]
Metselaar, Josbert M. (Corresponding author)
Lammers, Twan (Corresponding author)
[Contribution to a book, Journal Article]
Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery
In: Journal of controlled release, 328, 970-984, 2020
[DOI: 10.1016/j.jconrel.2020.09.013]
Wang, Yan
van Steenbergen, Mies J.
Beztsinna, Nataliia
Shi, Yang
Lammers, Twan
van Nostrum, Cornelus F.
Hennink, Wim E. (Corresponding author)
[Journal Article]
Polymeric Nanoparticles with Neglectable Protein Corona
In: Small : nano micro, 16 (18), 1907574, 2020
[DOI: 10.1002/smll.201907574]
Alberg, Irina
Kramer, Stefan
Schinnerer, Meike
Hu, Qizhi
Seidl, Christine
Leps, Christian
Drude, Natascha Ingrid
Möckel, Diana
Rijcken, Cristianne
Lammers, Twan
Diken, Mustafa
Maskos, Michael
Morsbach, Svenja
Landfester, Katharina
Tenzer, Stefan (Corresponding author)
Barz, Matthias (Corresponding author)
Zentel, Rudolf (Corresponding author)
[Journal Article]
Clinically established biodegradable long acting injectables : An industry perspective
In: Advanced drug delivery reviews, 167, 19-46, 2020
[DOI: 10.1016/j.addr.2020.11.008]
Nkanga, Christian Isalomboto
Fisch, Andreas
Rad-Malekshahi, Mazda
Romic, Marieta Duvnjak
Kittel, Birgit
Ullrich, Thomas
Wang, Jing
Krause, Rui Werner Maçedo
Adler, Sabine
Lammers, Twan
Hennink, Wim E.
Ramazani, Farshad (Corresponding author)
[Contribution to a book, Journal Article]
Lipids in disease pathology, diagnosis & therapy
In: Advanced drug delivery reviews, 159, 1-3, 2020
[DOI: 10.1016/j.addr.2020.11.006]
Lammers, Twan (Corresponding author)
Noels, Heidi
[Book]
Lipids in disease pathology, diagnosis & therapy
In: Advanced drug delivery reviews, 159, 390 Seiten, 2020
Lammers, Twan (Editor)
Noels, Heidi (Editor)
[Contribution to a book, Journal Article]
Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers
In: Pharmaceutics, 12 (6), 590, 2020
[DOI: 10.3390/pharmaceutics12060590]
Azzam, Menna
El Safy, Sara
Abdelgelil, Sarah A.
Weiskirchen, Ralf
Asimakopoulou, Anastasia
De Lorenzi, Federica
Lammers, Twan
Mansour, Samar
Tammam, Salma (Corresponding author)
[Journal Article]
Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells
In: Cellular signalling, 74, 109731, 2020
[DOI: 10.1016/j.cellsig.2020.109731]
Meurer, Steffen K. (Corresponding author)
Tezcan, Okan
Lammers, Twan
Weiskirchen, Ralf
[Contribution to a book, Journal Article]
Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine
In: Advanced materials, 32 (13), 1901989, 2019, 2020
[DOI: 10.1002/adma.201901989]
Adir, Omer
Poley, Maria
Chen, Gal
Froim, Sahar
Krinsky, Nitzan
Shklover, Jeny
Shainsky-Roitman, Janna
Lammers, Twan
Schroeder, Avi (Corresponding author)
[Journal Article]
Imaging-assisted anticancer nanotherapy
In: Theranostics, 10 (3), 956-967, 2020
[DOI: 10.7150/thno.38288]
Dasgupta, Anshuman
Biancacci, Ilaria
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
High-resolution 3D visualization of nanomedicine distribution in tumors
In: Theranostics, 10 (2), 880-897, 2019, 2020
[DOI: 10.7150/thno.37178]
Moss, Jennifer I. (Corresponding author)
Barjat, Hervé
Emmas, Sally-Ann
Strittmatter, Nicole
Maynard, Juliana
Goodwin, Richard J. A.
Storm, Gert
Lammers, Twan
Puri, Sanyogitta
Ashford, Marianne B.
Barry, Simon T.
[Journal Article]
CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence
In: Gastroenterology, 156 (6), 1877-1889.e4, 2019
[DOI: 10.1053/j.gastro.2019.01.247]
Mossanen, Jana C.
Kohlhepp, Marlene
Wehr, Alexander
Krenkel, Oliver
Liepelt, Anke
Roeth, Anjali A.
Möckel, Diana
Heymann, Felix
Lammers, Twan
Gassler, Nikolaus
Hermann, Juliane
Jankowski, Joachim
Neumann, Ulf P.
Luedde, Tom
Trautwein, Christian
Tacke, Frank
[Journal Article]
MR and PET-CT monitoring of tissue-engineered vascular grafts in the ovine carotid artery
In: Biomaterials : biomaterials reviews online, 216, 119228, 2019
[DOI: 10.1016/j.biomaterials.2019.119228]
Wolf, F.
Paefgen, V.
Winz, O.
Mertens, M.
Koch, S.
Gross-Weege, N.
Morgenroth, A.
Rix, A.
Schnoering, H.
Chalabi, K.
Jockenhoevel, S.
Lammers, T.
Mottaghy, F.
Kiessling, F.
Mela, P.
[Journal Article]
Combining Nanomedicine and Immunotherapy
In: Accounts of chemical research, 52 (6), 1543-1554, 2019
[DOI: 10.1021/acs.accounts.9b00148]
Shi, Yang
Lammers, Twan
[Journal Article]
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
In: Advanced drug delivery reviews, 138, 302-325, 2019
[DOI: 10.1016/j.addr.2019.01.005]
Dadfar, Seyed Mohammadali
Roemhild, Karolin
Drude, Natascha I.
von Stillfried, Saskia
Knüchel, Ruth
Kiessling, Fabian
Lammers, Twan
[Journal Article]
Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo
In: Biomaterials, 206, 49-60, 2019
[DOI: 10.1016/j.biomaterials.2019.03.025]
Ergen, Can
Niemietz, Patricia Maria
Heymann, Felix
Baues, Maike
Gremse, Felix
Pola, Robert
van Bloois, Louis
Storm, Gert
Kiessling, Fabian
Trautwein, Christian
Luedde, Tom
Lammers, Twan
Tacke, Frank
[Journal Article]
Setting standards to promote progress in bio-nano science
In: Nature nanotechnology, 14 (7), 626, 2019
[DOI: 10.1038/s41565-019-0497-8]
Lammers, Twan
Storm, Gert
[Journal Article]
Effect of neurokinin-1-receptor blockage on fracture healing in rats
In: Scientific reports, 9, 9744, 2019
[DOI: 10.1038/s41598-019-46278-6]
Hofman, Martijn
Rabenschlag, Frederik
Andruszkow, Hagen
Andruszkow, Julia
Möckel, Diana
Lammers, Twan
Kolejewska, Aneta
Kobbe, Philipp
Greven, Johannes
Teuben, Michel Paul Johan
Poeze, Martijn
Hildebrand, Frank
[Journal Article]
Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro
In: Nanotechnology, 30 (26), 264001, 2019
[DOI: 10.1088/1361-6528/ab0ce6]
Sadeghi, Negar
Kok, Robbert Jan
Bos, Clemens
Zandvliet, Maurice
Geerts, Willie J. C.
Storm, Gert
Moonen, Chrit T. W.
Lammers, Twan
Deckers, Roel
[Journal Article]
Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles
In: Pharmaceutics, 11 (9), 2019
[DOI: 10.3390/pharmaceutics11090433]
Ojha, Tarun
Pathak, Vertika
Drude, Natascha
Weiler, Marek
Rommel, Dirk
Rütten, Stephan
Geinitz, Bertram
van Steenbergen, Mies J.
Storm, Gert
Kiessling, Fabian
Lammers, Twan
[Journal Article]
3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics
In: Advanced materials, 31 (14), 1806590, 2019
[DOI: 10.1002/adma.201806590]
Heinrich, M. A.
Bansal, R.
Lammers, T.
Zhang, Y. S.
Schiffelers, R. M.
Prakash, J.
[Journal Article]
Smart cancer nanomedicine
In: Nature nanotechnology, 14 (11), 1007-1017, 2019
[DOI: 10.1038/s41565-019-0567-y]
van der Meel, Roy
Sulheim, Einar
Shi, Yang
Kießling, Fabian
Mulder, Willem J. M.
Lammers, Twan (Corresponding author)
[Journal Article]
Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy
In: Theranostics, 9 (26), 7981-8000, 2019
[DOI: 10.7150/thno.37568]
Saeed, Madiha
Gao, Jing
Shi, Yang
Lammers, Twan
Yu, Haijun
[Journal Article]
Bone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eels
In: Proceedings of the National Academy of Sciences of the United States of America, 116 (23), 11339-11344, 2019
[DOI: 10.1073/pnas.1817738116]
Freese, Marko (Corresponding author)
Rizzo, Larissa Y.
Pohlmann, Jan-Dag
Marohn, Lasse
Witten, Paul Eckhard
Gremse, Felix
Rütten, Stephan
Güvener, Nihan
Michael, Sabrina
Wysujack, Klaus
Lammers, Twan
Kießling, Fabian
Hollert, Henner
Hanel, Reinhold
Brinkmann, Markus
[Journal Article]
The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis
In: Frontiers in pharmacology, 10, 244, 2019
[DOI: 10.3389/fphar.2019.00244]
Hansel, Cordula (Corresponding author)
Erschfeld, Stephanie
Baues, Maike
Lammers, Twan
Weiskirchen, Ralf
Trautwein, Christian
Kroy, Daniela C.
Drescher, Hannah K.
[Journal Article]
Nanomedicine and macroscale materials in immuno-oncology
In: Chemical Society reviews : CSR, 48 (1), 351-381, 2019
[DOI: 10.1039/c8cs00473k]
Sun, Qingxue
Barz, Matthias
De Geest, Bruno G.
Diken, Mustafa
Hennink, Wim E.
Kießling, Fabian
Lammers, Twan (Corresponding author)
Shi, Yang (Corresponding author)
[Journal Article]
Macro-nanomedicine: Targeting the big picture
In: Journal of controlled release, 294, 372-375, 2018, 2019
[DOI: 10.1016/j.jconrel.2018.11.031]
Lammers, Twan (Corresponding author)
[Journal Article]
The CCR2 Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers
In: Cellular and Molecular Gastroenterology and Hepatology : CMGH, 7 (2), 371-390, 2019
[DOI: 10.1016/j.jcmgh.2018.10.007]
Bartneck, Matthias
Schrammen, Peter L.
Möckel, Diana
Govaere, Olivier
Liepelt, Anke
Krenkel, Oliver
Ergen, Can
McCain, Misti Vanette
Eulberg, Dirk
Luedde, Tom
Trautwein, Christian
Kiessling, Fabian
Reeves, Helen
Lammers, Twan
Tacke, Frank (Corresponding author)
[Contribution to a conference proceedings, Journal Article]
Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors
In: Journal of controlled release, 282, 25-34, 2018
[DOI: 10.1016/j.jconrel.2018.05.002]
Theek, Benjamin
Baues, Maike
Gremse, Felix
Pola, Robert
Pechar, Michal
Negwer, Inka
Koynov, Kaloian
Weber, Benjamin
Barz, Matthias
Jahnen-Dechent, Wilhelm
Storm, Gert
Kiessling, Fabian
Lammers, Twan (Corresponding author)
[Contribution to a conference proceedings, Journal Article]
Influence of cholesterol inclusion on the doxorubicin release characteristics of lysolipid-based thermosensitive liposomes
In: International journal of pharmaceutics, 548 (2), 778-782, 2017, 2018
[DOI: 10.1016/j.ijpharm.2017.11.002]
Sadeghi, Negar
Deckers, Roel
Ozbakir, Burcin
Akthar, Sohail
Kok, Robbert Jan
Lammers, Twan
Storm, Gert (Corresponding author)
[Journal Article]
Semi-Automated Segmentation of the Tumor Vasculature in Contrast-Enhanced Ultrasound Data
In: Ultrasound in medicine & biology, 44 (8), 1910-1917, 2018
[DOI: 10.1016/j.ultrasmedbio.2018.03.015]
Theek, Benjamin
Opačić, Tatjana
Lammers, Twan
Kiessling, Fabian (Corresponding author)
[Journal Article]
Imaging Nanomedicine-Based Drug Delivery : a Review of Clinical Studies
In: Molecular imaging & biology : MIB, 20 (5), 683-695, 2018
[DOI: 10.1007/s11307-018-1255-2]
Man, Francis
Lammers, Twan
de Rosales, Rafael T. M. (Corresponding author)
[Contribution to a book, Journal Article]
Tumor targeting via EPR: Strategies to enhance patient responses
In: Advanced drug delivery reviews, 130, 17-38, 2018
[DOI: 10.1016/j.addr.2018.07.007]
Golombek, Susanne K.
May, Jan-Niklas
Theek, Benjamin
Appold, Lia
Drude, Natascha Ingrid
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Sonopermeation to improve drug delivery to tumors: from fundamental understanding to clinical translation
In: Expert opinion on drug delivery, 15 (12), 1249-1261, 2018
[DOI: 10.1080/17425247.2018.1547279]
Snipstad, Sofie
Sulheim, Einar
de Lange Davies, Catharina
Moonen, Chrit
Storm, Gert
Kießling, Fabian
Schmid, Ruth (Corresponding author)
Lammers, Twan (Corresponding author)
[Journal Article]
Radiomic analysis of contrast-enhanced ultrasound data
In: Scientific reports, 8, 11359, 2018
[DOI: 10.1038/s41598-018-29653-7]
Theek, Benjamin
Opacic, Tatjana
Magnuska, Zuzanna
Lammers, Twan
Kiessling, Fabian (Corresponding author)
[Journal Article]
Advanced Ultrasound Technologies for Diagnosis and Therapy
In: Journal of nuclear medicine : JNM, 59 (5), 740-746, 2018
[DOI: 10.2967/jnumed.117.200030]
Rix, Anne
Lederle, Wiltrud
Theek, Benjamin
Lammers, Twan
Moonen, Chrit
Schmitz, Georg
Kießling, Fabian (Corresponding author)
[Journal Article]
A computational and experimental study to develop E-selectin targeted peptides for molecular imaging applications
In: Future medicinal chemistry, 10 (23), 2695-2711, 2018
[DOI: 10.4155/fmc-2018-0244]
Fernandes, Ana Carina
Liu, Mengjiao
Sorbo, Teresa
Appold, Lia Christina
Ilbert, Marianne
Ferracci, Géraldine
Kießling, Fabian
Branco, Ricardo J. F.
Lammers, Twan (Corresponding author)
Iranzo, Olga (Corresponding author)
[Journal Article]
The multikinase inhibitor regorafenib decreases angiogenesis and improves portal hypertension
In: OncoTarget : open access impact journal, 9 (90), 36220-36237, 2018
[DOI: 10.18632/oncotarget.26333]
Uschner, Frank Erhard
Schueller, Florian
Nikolova, Ivelina
Klein, Sabine
Schierwagen, Robert
Magdaleno, Fernando
Gröschl, Stefanie
Loosen, Sven
Ritz, Thomas
Roderburg, Christoph
Vucur, Michael
Kristiansen, Glen
Lammers, Twan
Lüdde, Tom
Trebicka, Jonel (Corresponding author)
[Journal Article]
Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice
In: OncoTarget : open access impact journal, 9 (27), 18682-18697, 2018
[DOI: 10.18632/oncotarget.24588]
Simón-Gracia, Lorena (Corresponding author)
Scodeller, Pablo
Fuentes, Sergio Salazar
Vallejo, Vanessa Gómez
Ríos, Xabier
San Sebastián, Eneko
Sidorenko, Valeria
Di Silvio, Desiré
Suck, Meina
De Lorenzi, Federica
Rizzo, Larissa Y.
von Stillfried, Saskia
Kilk, Kalle
Lammers, Twan
Moya, Sergio E. (Corresponding author)
Teesalu, Tambet
[Journal Article]
c-Met Signaling Protects from Nonalcoholic Steatohepatitis- (NASH-) Induced Fibrosis in Different Liver Cell Types
In: Oxidative medicine and cellular longevity, 2018, 6957497, 2018
[DOI: 10.1155/2018/6957497]
Drescher, Hannah K.
Schumacher, Fabienne
Schenker, Teresa
Baues, Maike
Lammers, Twan
Hieronymus, Thomas
Trautwein, Christian
Streetz, Konrad L.
Kroy, Daniela C. (Corresponding author)
[Journal Article]
PLGA-Based Nanoparticles in Cancer Treatment
In: Frontiers in pharmacology, 9, 1260, 2018
[DOI: 10.3389/fphar.2018.01260]
Rezvantalab, Sima
Drude, Natascha
Moraveji, Mostafa Keshavarz (Corresponding author)
Güvener, Nihan
Koons, Emily Kate
Shi, Yang
Lammers, Twan
Kießling, Fabian (Corresponding author)
[Journal Article]
Motion model ultrasound localization microscopy for preclinical and clinical multiparametric tumor characterization
In: Nature Communications, 9 (1), 1527, 2018
[DOI: 10.1038/s41467-018-03973-8]
Opacic, Tatjana
Dencks, Stefanie
Theek, Benjamin
Piepenbrock, Marion
Ackermann, Dimitri
Rix, Anne
Lammers, Twan
Stickeler, Elmar
Delorme, Stefan
Schmitz, Georg (Corresponding author)
Kießling, Fabian (Corresponding author)
[Contribution to a book, Journal Article]
In Vitro Evaluation of Anti-Aggregation and Degradation Behavior of PEGylated Polymeric Nanogels under In Vivo Like Conditions
In: Macromolecular bioscience, 18 (1), 1700127, 2017, 2018
[DOI: 10.1002/mabi.201700127]
Chen, Yinan
Dakwar, George R.
Braeckmans, Kevin
Lammers, Twan
Hennink, Wim E. (Corresponding author)
Metselaar, Josbert M. (Corresponding author)
[Journal Article]
Multimodal [GdO]+[ICG]− Nanoparticles for Optical, Photoacoustic, and Magnetic Resonance Imaging
In: Chemistry of materials, 29 (8), 3547-3554, 2017
[DOI: 10.1021/acs.chemmater.6b05406]
Poß, Marieke
Tower, Robert J.
Napp, Joanna
Appold, Lia
Lammers, Twan
Alves, Frauke
Glüer, Claus-Christian
Boretius, Susann
Feldmann, Claus (Corresponding author)
[Abstract, Contribution to a conference proceedings, Journal Article]
CCL2-dependent monocyte recruitment contributes to a tumor-promoting microenvironment in a combined fibrosis-HCC modelung
In: Journal of hepatology, 66 (1, Supplement), SAT-126, 2017
[DOI: 10.1016/S0168-8278(17)31715-4]
Schrammen, P. L. (Corresponding author)
Bartneck, Matthias
Möckel, D.
Liepelt, Anke
Eulberg, Dirk
Longerich, Thomas
Lüdde, Tom
Trautwein, Christian
Lammers, Twan
Tacke, Frank
[Contribution to a conference proceedings, Journal Article]
PBCA-based polymeric microbubbles for molecular imaging and drug delivery
In: Journal of controlled release, 259, 128-135, 2017
[DOI: 10.1016/j.jconrel.2017.03.006]
Koczera, Patrick
Appold, Lia
Shi, Yang
Liu, Mengjiao
Dasgupta, Anshuman
Pathak, Vertika
Ojha, Tarun
Fokong, Stanley
Wu, Zhuojun
van Zandvoort, Marc
Iranzo, Olga
Kuehne, Alexander J. C.
Pich, Andrij
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers
In: ACS nano, 11 (10), 9689-9700, 2017
[DOI: 10.1021/acsnano.7b04630]
Bartneck, Matthias
Schlößer, Christopher Thorsten
Barz, Matthias
Zentel, Rudolf
Trautwein, Christian
Lammers, Twan
Tacke, Frank
[Journal Article]
Targeting CCl4‐induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice
In: Hepatology : official journal of the American Association for the Study of Liver Diseases, 66 (4), 1242-1257, 2017
[DOI: 10.1002/hep.29275]
Bangen, Jörg-Martin
Hammerich, Linda
Sonntag, Roland
Baues, Maike
Haas, Ute
Lambertz, Daniela
Longerich, Thomas
Lammers, Twan
Tacke, Frank
Trautwein, Christian
Liedtke, Christian (Corresponding author)
[Contribution to a book, Journal Article]
Fibrosis imaging: Current concepts and future directions
In: Advanced drug delivery reviews, 121, 9-26, 2017
[DOI: 10.1016/j.addr.2017.10.013]
Baues, Maike
Dasgupta, Anshuman
Ehling, Josef
Prakash, Jai
Boor, Peter
Tacke, Frank
Kiessling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Challenges and strategies in anti-cancer nanomedicine development: An industry perspective
In: Advanced drug delivery reviews, 108, 25-38, 2017
[DOI: 10.1016/j.addr.2016.04.025]
Hare, Jennifer I. (Corresponding author)
Lammers, Twan
Ashford, Marianne B.
Puri, Sanyogitta
Storm, Gert
Barry, Simon T.
[Contribution to a book, Journal Article]
Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors☆
In: Advanced drug delivery reviews, 119, 44-60, 2017
[DOI: 10.1016/j.addr.2017.07.007]
Ojha, Tarun
Pathak, Vertika
Shi, Yang
Hennink, Wim E.
Moonen, Chrit T. W.
Storm, Gert
Kiessling, Fabian (Corresponding author)
Lammers, Twan (Corresponding author)
[Journal Article]
Enhancing Tumor Penetration of Nanomedicines
In: Biomacromolecules, 18 (5), 1449-1459, 2017
[DOI: 10.1021/acs.biomac.7b00068]
Sun, Qingxue
Ojha, Tarun
Kiessling, Fabian
Lammers, Twan
Shi, Yang
[Journal Article]
Photoacoustic imaging of tumor targeting with riboflavin-functionalized theranostic nanocarriers
In: International journal of nanomedicine, 12, 3813-3825, 2017
[DOI: 10.2147/IJN.S125192]
Beztsinna, Nataliia
Tsvetkova, Yoanna
Jose, Jithin
Rhourri-Frih, Boutayna
Al Rawashdeh, Wa'el
Lammers, Twan
Kiessling, Fabian (Corresponding author)
Bestel, Isabelle (Corresponding author)
[Journal Article]
Singlet oxygen-responsive micelles for enhanced photodynamic therapy
In: Journal of controlled release, 260, 12-21, 2017
[DOI: 10.1016/j.jconrel.2017.05.025]
Li, Xiaodan
Gao, Min
Xin, Keting
Zhang, Ling
Ding, Dan
Kong, Deling
Wang, Zheng
Shi, Yang
Kiessling, Fabian
Lammers, Twan
Cheng, Jianjun
Zhao, Yanjun (Corresponding author)
[Journal Article]
Recent advances in ultrasound-based diagnosis and therapy with micro- and nanometer-sized formulations
In: Methods, 130, 4-13, 2017
[DOI: 10.1016/j.ymeth.2017.05.018]
Güvener, Nihan
Appold, Lia
de Lorenzi, Federica
Golombek, Susanne K.
Rizzo, Larissa Y.
Lammers, Twan
Kiessling, Fabian
[Journal Article]
Tumor-targeted nanomedicines for cancer theranostics
In: Pharmacological research, 115, 87-95, 2017
[DOI: 10.1016/j.phrs.2016.11.014]
Arranja, Alexandra G.
Pathak, Vertika
Lammers, Twan
Shi, Yang
[Journal Article]
Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers
In: Nano letters, 17 (8), 4665-4674, 2017
[DOI: 10.1021/acs.nanolett.7b01171]
Tsvetkova, Yoanna (Corresponding author)
Beztsinna, Nataliia
Baues, Maike
Klein, Dionne
Rix, Anne
Golombek, Susanne K.
Al Rawashdeh, Wa'el
Gremse, Felix
Barz, Matthias
Koynov, Kaloian
Banala, Srinivas
Lederle, Wiltrud
Lammers, Twan
Kiessling, Fabian
[Journal Article]
Targeting iron metabolism in drug discovery and delivery
In: Nature reviews / Drug discovery, 16 (6), 400-423, 2017
[DOI: 10.1038/nrd.2016.248]
Crielaard, Bart J.
Lammers, Twan
Rivella, Stefano
[Contribution to a book, Journal Article]
Physicochemical Characterization of the Shell Composition of PBCA-Based Polymeric Microbubbles
In: Macromolecular bioscience, 17 (10), 1700002, 2017
[DOI: 10.1002/mabi.201700002]
Appold, Lia
Shi, Yang
Rütten, Stephan
Kühne, Alexander J. C.
Pich, Andrij
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Automated Generation of Reliable Blood Velocity Parameter Maps from Contrast-Enhanced Ultrasound Data
In: Contrast media & molecular imaging, 2017, 2098324, 2017
[DOI: 10.1155/2017/2098324]
Theek, Benjamin
Opacic, Tatjana
Möckel, Diana
Schmitz, Georg
Lammers, Twan
Kießling, Fabian (Corresponding author)
[Journal Article]
Status and trends in the development of clinical diagnostic agents
In: Wiley interdisciplinary reviews / Nanomedicine and Nanobiotechnology, 9 (4), e1441, 2016, 2017
[DOI: 10.1002/wnan.1441]
Opacic, Tatjana
Paefgen, Vera
Lammers, Twan
Kießling, Fabian (Corresponding author)
[Journal Article]
Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin
In: Nanoscale, 9 (29), 10404-10419, 2017
[DOI: 10.1039/C7NR03592F]
Chen, Y. (Corresponding author)
Tezcan, O.
Li, D.
Beztsinna, N.
Lou, B.
Etrych, T.
Ulbrich, K.
Metselaar, J. M.
Lammers, T.
Hennink, W. E. (Corresponding author)
[Journal Article]
Physico-Chemical Strategies to Enhance Stability and Drug Retention of Polymeric Micelles for Tumor-Targeted Drug Delivery
In: Macromolecular bioscience, 17 (1), 1600160, 2016, 2017
[DOI: 10.1002/mabi.201600160]
Shi, Yang
Lammers, Twan
Storm, Gert
Hennink, Wim E. (Corresponding author)
[Journal Article]
Noninvasive Assessment of Elimination and Retention using CT-FMT and Kinetic Whole-body Modeling
In: Theranostics, 7 (6), 1499-1510, 2017
[DOI: 10.7150/thno.17263]
Al Rawashdeh, Wa'el
Zuo, Simin
Melle, Andrea
Appold, Lia
Koletnik, Susanne
Tsvetkova, Yoanna
Beztsinna, Nataliia
Pich, Andrij
Lammers, Twan
Kießling, Fabian
Gremse, Felix (Corresponding author)
[Journal Article]
Fluorinated polyurethane scaffolds for 19F magnetic resonance imaging
In: Chemistry of materials, 29 (7), 2669-2671, 2017
[DOI: 10.1021/acs.chemmater.6b04649]
Lammers, Twan (Corresponding author)
Mertens, Marianne Elisabeth
Schuster, Philipp
Rahimi, Khosrow
Shi, Yang
Schulz, Volkmar
Kühne, Alexander J. C.
Jockenhövel, Stefan
Kießling, Fabian (Corresponding author)
[Journal Article]
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
In: Biomaterials, 114, 106-120, 2016, 2017
[DOI: 10.1016/j.biomaterials.2016.11.009]
Ergen, Can
Heymann, Felix
Al Rawashdeh, Wa'el
Gremse, Felix
Bartneck, Matthias
Panzer, Ulf
Pola, Robert
Pechar, Michal
Storm, Gert
Mohr, Nicole
Barz, Matthias
Zentel, Rudolf
Kießling, Fabian
Trautwein, Christian
Lammers, Twan (Corresponding author)
Tacke, Frank (Corresponding author)
[Journal Article]
Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration
In: Angewandte Chemie / International edition, 56 (5), 1416-1421, 2016, 2017
[DOI: 10.1002/anie.201610395]
Moog, Kai E.
Barz, Matthias
Bartneck, Matthias
Beceren-Braun, Figen
Mohr, Nicole
Wu, Zhuojun
Braun, Lydia
Dernedde, Jens
Liehn, Elisa Anamaria
Tacke, Frank
Lammers, Twan
Kunz, Horst
Zentel, Rudolf (Corresponding author)
[Contribution to a conference proceedings, Journal Article]
Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications
In: Journal of controlled release, 244 (Pt B), 314-325, 2016
[DOI: 10.1016/j.jconrel.2016.07.012]
Hu, Qizhi
Rijcken, Cristianne J. F.
van Gaal, Ethlinn
Brundel, Paul
Kostkova, Hana
Etrych, Tomas
Weber, Benjamin
Barz, Matthias
Kießling, Fabian
Prakash, Jai
Storm, Gert
Hennink, Wim E.
Lammers, Twan (Corresponding author)
[Journal Article]
Imalytics Preclinical: Interactive Analysis of Biomedical Volume Data
In: Theranostics, 6 (3), 328-341, 2016
[DOI: 10.7150/thno.13624]
Gremse, Felix (Corresponding author)
Stärk, Marius
Ehling, Josef Ludger Anton
Menzel, Jan Robert
Lammers, Twan
Kießling, Fabian
[Contribution to a conference proceedings, Journal Article]
Sonoporation enhances liposome accumulation and penetration in tumors with low EPR
In: Journal of controlled release, 231, 77-85, 2016
[DOI: 10.1016/j.jconrel.2016.02.021]
Theek, Benjamin
Baues, Maike
Ojha, Tarun
Möckel, Diana
Veettil, Seena Koyadan
Steitz, Julia
van Bloois, Louis
Storm, Gert
Kießling, Fabian (Corresponding author)
Lammers, Twan (Corresponding author)
[Contribution to a conference proceedings, Journal Article]
Non-invasive molecular imaging of kidney fibrosis
In: Nephrology, dialysis, transplantation, 31 (suppl_1), i38-i38, 2016
[DOI: 10.1093/ndt/gfw134.02]
Ehling, Josef Ludger Anton
Klinkhammer, Barbara Mara
Sun, Qinxue
Baues, Maike
Kießling, Fabian
Flöge, Jürgen
Lammers, Twan
Boor, Peter
[Journal Article]
Histidine-rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease
In: Hepatology : official journal of the American Association for the Study of Liver Diseases, 63 (4), 1310-1324, 2016
[DOI: 10.1002/hep.28418]
Bartneck, Matthias
Fech, Viktor
Ehling, Josef Ludger Anton
Govaere, Olivier
Warzecha, Klaudia Theresa
Hittatiya, Kanishka
Vucur, Mihael
Gautheron, Jérémie
Lüdde, Tom
Trautwein, Christian
Lammers, Twan
Roskams, Tania
Jahnen-Dechent, Wilhelm
Tacke, Frank (Corresponding author)
[Journal Article]
In situ validation of VEGFR-2 and αvß3 integrin as targets for breast lesion characterization
In: Angiogenesis, 19 (2), 245-254, 2016
[DOI: 10.1007/s10456-016-9499-4]
Ehling, Josef Ludger Anton
Misiewicz, Matthias
von Stillfried, Saskia
Möckel, Diana
Bzyl, Jessica
Pochon, Sibylle
Lederle, Wiltrud
Knüchel-Clarke, Ruth
Lammers, Twan
Palmowski, Moritz
Kießling, Fabian (Corresponding author)
[Journal Article]
Erratum to: In situ validation of VEGFR-2 and αvß3 integrin as targets for breast lesion characterization
In: Angiogenesis, 19 (3), 449-449, 2016
[DOI: 10.1007/s10456-016-9507-8]
Ehling, Josef Ludger Anton
Misiewicz, Matthias
von Stillfried, Saskia
Möckel, Diana
Bzyl, Jessica
Pochon, Sibylle
Lederle, Wiltrud
Knüchel-Clarke, Ruth
Lammers, Twan
Palmowski, Moritz
Kießling, Fabian (Corresponding author)
[Journal Article]
Amphiphilic Phospholipid-Based Riboflavin Derivatives for Tumor Targeting Nanomedicines
In: Bioconjugate chemistry, 27 (9), 2048-2061, 2016
[DOI: 10.1021/acs.bioconjchem.6b00317]
Beztsinna, Nataliia
Tsvetkova, Yoanna
Bartneck, Matthias
Lammers, Twan
Kießling, Fabian (Corresponding author)
Bestel, Isabelle (Corresponding author)
[Journal Article]
Locoregional cancer therapy using polymer-based drug depots
In: Drug discovery today, 21 (4), 640-647, 2016
[DOI: 10.1016/j.drudis.2016.02.014]
Ramazani, Farshad
van Nostrum, Cornelis F.
Storm, Gert
Kießling, Fabian
Lammers, Twan
Hennink, Wim E.
Kok, Robbert J. (Corresponding author)
[Journal Article]
Targeting cellular and microenvironmental multidrug resistance
In: Expert opinion on drug delivery, 13 (9), 1199-1202, 2016
[DOI: 10.1080/17425247.2016.1214570]
Tezcan, Okan
Ojha, Tarun
Storm, Gert
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Strategies for encapsulation of small hydrophilic and amphiphilic drugs in PLGA microspheres : State-of-the-art and challenges
In: International journal of pharmaceutics, 499 (1/2), 358-367, 2016
[DOI: 10.1016/j.ijpharm.2016.01.020]
Ramazani, Farshad
Chen, Weiluan
van Nostrum, Cornelis F.
Storm, Gert
Kießling, Fabian
Lammers, Twan
Hennink, Wim E.
Kok, Robbert J. (Corresponding author)
[Journal Article]
Polymeric Nanogels with Tailorable Degradation Behavior
In: Macromolecular bioscience, 16 (8), 1122-1137, 2016
[DOI: 10.1002/mabi.201600031]
Chen, Yinan
van Steenbergen, Mies J.
Li, Dandan
van de Dikkenberg, Joep B.
Lammers, Twan
van Nostrum, Cornelus F.
Metselaar, Josbert M.
Hennink, Wim E. (Corresponding author)
[Journal Article]
Cancer nanomedicine: Is targeting our target?
In: Nature reviews / Materials, 1 (9), 2016
[DOI: 10.1038/natrevmats.2016.69]
Lammers, Twan (Corresponding author)
Kießling, Fabian
Ashford, Marianne
Hennink, Wim
Crommelin, Daan (Corresponding author)
Storm, Gert
[Journal Article]
Squamous Cell Carcinoma Xenografts: Use of VEGFR2-targeted Microbubbles for Combined Functional and Molecular US to Monitor Antiangiogenic Therapy Effects
In: Radiology, 278 (2), 430-440, 2015, 2016
[DOI: 10.1148/radiol.2015142899]
Baetke, Sarah C.
Rix, Anne
Tranquart, François
Schneider, Richard
Lammers, Twan
Kießling, Fabian (Corresponding author)
Lederle, Wiltrud
[Journal Article]
Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis
In: Frontiers in pharmacology, 7, 33, 2016
[DOI: 10.3389/fphar.2016.00033]
Schon, Hans-Theo
Bartneck, Matthias
Borkham-Kamphorst, Erawan
Nattermann, Jacob
Lammers, Twan
Tacke, Frank
Weiskirchen, Ralf (Corresponding author)
[Journal Article]
Refinement of adsorptive coatings for fluorescent riboflavin-receptor-targeted iron oxide nanoparticles
In: Contrast media & molecular imaging, 11 (1), 47-54, 2016
[DOI: 10.1002/cmmi.1657]
Tsvetkova, Yoanna
Beztsinna, Nataliia
Jayapaul, Jabadurai
Weiler, Marek
Arns, Susanne
Shi, Yang
Lammers, Twan
Kießling, Fabian (Corresponding author)
[Journal Article]
Quantitative Micro-Computed Tomography Imaging of Vascular Dysfunction in Progressive Kidney Diseases
In: Journal of the American Society of Nephrology, 27 (2), 520-532, 2016
[DOI: 10.1681/ASN.2015020204]
Ehling, Josef Ludger Anton
Bábícková, Janka
Gremse, Felix
Klinkhammer, Barbara M.
Baetke, Sarah C.
Knüchel-Clarke, Ruth
Kießling, Fabian
Flöge, Jürgen
Lammers, Twan (Corresponding author)
Boor, Peter (Corresponding author)
[Journal Article]
Micro-computed tomography (μCT) as a novel method in ecotoxicology : determination of morphometric and somatic data in rainbow trout (Oncorhynchus mykiss)
In: The science of the total environment, 543, 135-139, 2015, 2016
[DOI: 10.1016/j.scitotenv.2015.11.020]
Brinkmann, Markus (Corresponding author)
Rizzo, Larissa Y.
Lammers, Twan
Gremse, Felix
Schiwy, Sabrina
Kießling, Fabian
Hollert, Henner (Corresponding author)
[Abstract, Contribution to a conference proceedings, Journal Article]
Selectin-targeting nanoparticles for immunomodulatory therapy of liver diseases
In: Journal of hepatology, 62 (Supplement 2), P0493, 2015
[DOI: 10.1016/S0168-8278(15)30701-7]
Bartneck, Matthias (Corresponding author)
Schlößer, Christopher Thorsten
Warzecha, Klaudia Theresa
Lammers, Twan
Trautwein, Christian
Moog, K.
Kunz, H.
Zentel, R.
Barz, M.
Tacke, Frank
[Journal Article]
Hybrid µCT-FMT imaging and image analysis
In: Journal of visualized experiments (100), e52770, 2015
[DOI: 10.3791/52770]
Gremse, Felix
Doleschel, Dennis
Zafarnia, Sara
Babler, Anne
Jahnen-Dechent, Willi
Lammers, Twan
Lederle, Wiltrud
Kießling, Fabian (Corresponding author)
[Journal Article]
Applications of nanoparticles for diagnosis and therapy of cancer
In: The British journal of radiology, 88 (1054), 20150207, 2015
[DOI: 10.1259/bjr.20150207]
Baetke, S. C.
Lammers, T.
Kiessling, Fabian
[Journal Article]
Noninvasive Imaging of Nanomedicines and Nanotheranostics: Principles, Progress, and Prospects
In: Chemical reviews, 115 (19), 10907-10937, 2015
[DOI: 10.1021/cr500314d]
Kunjachan, Sijumon
Ehling, Josef
Storm, Gert
Kießling, Fabian (Corresponding author)
Lammers, Twan (Corresponding author)
[Journal Article]
Sunitinib microspheres based on [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers for ocular drug delivery
In: European journal of pharmaceutics and biopharmaceutics, 95 (Pt B), 368-377, 2015
[DOI: 10.1016/j.ejpb.2015.02.011]
Ramazani, F.
Hiemstra, C.
Steendam, R.
Kazazi-Hyseni, F.
van Nostrum, C. F.
Storm, G.
Kiessling, Fabian
Lammers, T.
Hennink, W. E.
Kok, R. J. (Corresponding author)
[Journal Article]
Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles
In: ACS nano, 9 (4), 3740-3752, 2015
[DOI: 10.1021/acsnano.5b00929]
Shi, Yang
van der Meel, Roy
Theek, Benjamin
Oude Blenke, Erik
Pieters, Ebel H. E.
Fens, Marcel H. A. M.
Ehling, Josef
Schiffelers, Raymond M.
Storm, Gert
van Nostrum, Cornelus F.
Lammers, Twan
Hennink, Wim E. (Corresponding author)
[Journal Article]
Long circulating and stable polymeric micelles for targeted delivery of paclitaxel
In: Journal of controlled release, 213, e127-e128, 2015
[DOI: 10.1016/j.jconrel.2015.05.215]
Shi, Yang (Corresponding author)
Lammers, Twan
van Nostrum, Cornelus
Hennink, Wim E.
[Journal Article]
Image-guided drug delivery : preclinical applications and clinical translation
In: Expert opinion on drug delivery, 12 (8), 1203-1207, 2015
[DOI: 10.1517/17425247.2015.1059420]
Ojha, Tarun
Rizzo, Larissa
Storm, Gert
Kiessling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Role of Platelet-Derived Growth Factor-CC in Capillary Rarefaction in Renal Fibrosis
In: The American journal of pathology, 185 (8), 2132-2142, 2015
[DOI: 10.1016/j.ajpath.2015.04.022]
Boor, Peter (Corresponding author)
Babickova, Janka
Steegh, Floor
Hautvast, Petra
Martin, Ina V.
Djudjaj, Sonja
Nakagawa, Taizo
Ehling, Josef
Gremse, Felix
Bücher, Eva
Eriksson, Ulf
van Roeyen, Claudia R. C.
Eitner, Frank
Lammers, Twan
Floege, Jürgen
Peutz-Kootstra, Carine J.
Ostendorf, Tammo
[Journal Article]
Water-soluble dopamine-based polymers for photoacoustic imaging
In: Chemical communications, 51 (28), 6084-6087, 2015, 2017
[DOI: 10.1039/C5CC00039D]
Repenko, Tatjana
Fokong, Stanley
De Laporte, Laura
Go, Dennis
Kießling, Fabian
Lammers, Twan
Kuehne, Alexander J. C. (Corresponding author)
[Journal Article]
Formulation and characterization of microspheres loaded with imatinib for sustained delivery
In: International journal of pharmaceutics, 482 (1-2), 123-130, 2015
[DOI: 10.1016/j.ijpharm.2015.01.043]
Ramazani, F.
Chen, W.
Van Nostrum, C. F.
Storm, G.
Kiessling, Fabian
Lammers, T.
Hennink, W. E.
Kok, R. J. (Corresponding author)
[Journal Article]
Flexible and Modular MPI Simulation Framework and Its Use in Modeling a μ MPI
In: IEEE transactions on magnetics, 51 (2), 1-4, 2015
[DOI: 10.1109/TMAG.2014.2329733]
Straub, Marcel (Corresponding author)
Lammers, Twan
Kiessling, Fabian
Schulz, Volkmar
[Journal Article]
A Field Cancellation Signal Extraction Method for Magnetic Particle Imaging
In: IEEE transactions on magnetics, 51 (2), 1-4, 2015
[DOI: 10.1109/TMAG.2014.2325852]
Schulz, Volkmar (Corresponding author)
Straub, Marcel
Mahlke, Max
Hubertus, Simon
Lammers, Twan
Kiessling, Fabian
[Journal Article]
Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth In Vivo
In: The prostate, 75 (8), 815-824, 2015
[DOI: 10.1002/pros.22963]
Kroon, Jan (Corresponding author)
Buijs, Jeroen T.
van der Horst, Geertje
Cheung, Henry
van der Mark, Maaike
van Bloois, Louis
Rizzo, Larissa Y.
Lammers, Twan
Pelger, Rob C.
Storm, Gert
van der Pluijm, Gabri
Metselaar, Josbert M.
[Journal Article]
Core-crosslinked polymeric micelles : Principles, preparation, biomedical applications and clinical translation
In: Nano today, 10 (1), 93-117, 2015
[DOI: 10.1016/j.nantod.2015.01.005]
Talelli, Marina
Barz, Matthias
Rijcken, Cristianne J. F.
Kießling, Fabian
Hennink, Wim E.
Lammers, Twan (Corresponding author)
[Journal Article]
Enhanced In Vitro and In Vivo Cellular Imaging with Green Tea Coated Water-Soluble Iron Oxide Nanocrystals
In: ACS applied materials & interfaces, 7 (12), 6530-6540, 2015
[DOI: 10.1021/am508404t]
Xiao, Lisong
Mertens, Marianne
Wortmann, Laura
Kremer, Silke
Valldor, Martin
Lammers, Twan
Kießling, Fabian
Mathur, Sanjay (Corresponding author)
[Journal Article]
USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts
In: Biomaterials, 39, 155-163, 2015
[DOI: 10.1016/j.biomaterials.2014.10.076]
Mertens, Marianne E.
Koch, Sabine
Schuster, Philipp
Wehner, Jakob
Wu, Zhuojun
Gremse, Felix
Schulz, Volkmar
Rongen, Lisanne
Wolf, Frederic
Frese, Julia
Gesché, Valentine
van Zandvoort, Marc A. M. J.
Mela, Petra
Jockenhövel, Stefan (Corresponding author)
Kießling, Fabian (Corresponding author)
Lammers, Twan (Corresponding author)
[Journal Article]
Decationized polyplexes for gene delivery
In: Expert opinion on drug delivery, 507-512, 2014
[DOI: 10.1517/17425247.2015.988136]
Novo, Luís
Mastrobattista, Enrico
van Nostrum, Cornelus F.
Lammers, Twan
Hennink, Wim E. (Corresponding author)
[Journal Article]
The Theranostic Path to Personalized Nanomedicine
In: Clinical and translational imaging, 2 (1), 66-76, 2014
[DOI: 10.1007/s40336-014-0051-5]
Theek, Benjamin
Rizzo, Larissa Y.
Ehling, Josef
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases
In: Biomaterials, 37, 367-382, 2014
[DOI: 10.1016/j.biomaterials.2014.10.030]
Bartneck, M.
Scheyda, K. M.
Warzecha, K. T.
Rizzo, L. Y.
Hittatiya, K.
Luedde, T.
Storm, G.
Trautwein, C.
Lammers, T.
Tacke, F. (Corresponding author)
[Journal Article]
FMN-coated fluorescent USPIO for cell labeling and non-invasive MR imaging in tissue engineering
In: Theranostics, 4 (10), 1002-1013, 2014
[DOI: 10.7150/thno.8763]
Mertens, Marianne E.
Frese, Julia
Bölükbas, Deniz Ali
Hrdlicka, Ladislav
Golombek, Susanne
Koch, Sabine
Mela, Petra
Jockenhövel, Stefan
Kiessling, Fabian (Corresponding author)
Lammers, Twan (Corresponding author)
[Contribution to a book, Journal Article]
Liposomal corticosteroids for the treatment of inflammatory disorders and cancer
In: Journal of controlled release, 190, 624-636, 2014
[DOI: 10.1016/j.jconrel.2014.05.039]
Ozbakir, B.
Crielaard, B. J.
Metselaar, Josbert M.
Storm, G.
Lammers, T.
[Contribution to a book, Journal Article, Poster]
Non-invasive monitoring of tissue-engineered vascular endothelium
In: Mitteilungen / Institut für Textiltechnik, 60.2013, 1 S., 2014
Frese, Julia (Corresponding author)
Hrdlicka, Ladislav
Mertens, M. E.
Rongen, Lisanne
Koch, Sabine
Schuster, Philipp
Gesché, Valentine
Lammers, Twan
Mela, Petra
Kiessling, Stephan
Jockenhövel, Stefan
[Contribution to a conference proceedings, Journal Article]
Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy
In: Journal of controlled release, 195, 162-175, 2014
[DOI: 10.1016/j.jconrel.2014.08.028]
Novo, Luís
Rizzo, Larissa Y.
Golombek, Susanne K.
Dakwar, George R.
Lou, Bo
Remaut, Katrien
Mastrobattista, Enrico
van Nostrum, Cornelus F.
Jahnen-Dechent, Wilhelm
Kießling, Fabian
Braeckmans, Kevin
Lammers, Twan
Hennink, Wim E. (Corresponding author)
[Journal Article]
Nanoparticles for Imaging : Top or Flop?
In: Radiology, 273 (1), 10-28, 2014
[DOI: 10.1148/radiol.14131520]
Kießling, Fabian (Corresponding author)
Mertens, Marianne E.
Grimm, Jan
Lammers, Twan
[Journal Article]
Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages
In: Nanomedicine / Nanotechnology, biology and medicine, 10 (6), 1209-1220, 2014
[DOI: 10.1016/j.nano.2014.02.011]
Bartneck, Matthias (Corresponding author)
Peters, Franziska Marie
Warzecha, Klaudia Theresa
Bienert, Michaela
van Bloois, Louis
Trautwein, Christian
Lammers, Twan
Tacke, Frank
[Journal Article]
Absorption Reconstruction Improves Biodistribution Assessment of Fluorescent Nanoprobes Using Hybrid Fluorescence-mediated Tomography
In: Theranostics, 4 (10), 960-971, 2014
[DOI: 10.7150/thno.9293]
Gremse, Felix (Corresponding author)
Theek, Benjamin
Kunjachan, Sijumon
Lederle, Wiltrud
Pardo, Alessa
Barth, Stefan
Lammers, Twan
Naumann, Uwe
Kießling, Fabian
[Contribution to a book, Journal Article]
Recent advances in molecular, multimodal and theranostic ultrasound imaging
In: Advanced drug delivery reviews, 72, 15-27, 2014
[DOI: 10.1016/j.addr.2013.11.013]
Kießling, Fabian (Corresponding author)
Fokong, Stanley
Bzyl, Jessica
Lederle, Wiltrud
Palmowski, Moritz
Lammers, Twan
[Abstract, Contribution to a conference proceedings, Journal Article]
Non-invasive monitoring of tissue-engineered vascular graft in the adult sheep model
In: Journal of tissue engineering and regenerative medicine, 8 (Suppl. 1), Poster presentations, 394-394, 2014
Wolf, Frederic
Koch, Sabine
Mertens, Marianne E.
Gesché, Valentine
Schuster, Philipp
Frese, Julia
Lammers, Twan
Kießling, Fabian
Mela, Petra
Jockenhövel, Stefan
[Journal Article]
In Vitro, In Vivo and In Silico Analysis of the Anticancer and Estrogen-like Activity of Guava Leaf Extracts
In: Current medicinal chemistry, 21 (20), 2322-2330, 2014
[DOI: 10.2174/0929867321666140120120031]
Rizzo, Larissa Y. (Corresponding author)
Longato, Giovanna Barbarini
Ruiz, A. Lt. G.
Tinti, S. V.
Possenti, A.
Vendramini-Costa, Débora Barbosa
Sartoratto, A.
Figueira, G. M.
Silva, F. L. N.
Eberlin, M. N.
Souza, T. A. C. B.
Murakami, M. T.
Rizzo, E.
Foglio, M. A.
Kießling, Fabian
Lammers, Twan
Carvalho, J. E.
[Journal Article]
Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging
In: Journal of controlled release, 182, 83-89, 2014
[DOI: 10.1016/j.jconrel.2014.03.007]
Theek, Benjamin
Gremse, Felix
Kunjachan, Sijumon
Fokong, Stanley
Pola, Robert
Pechar, Michal
Deckers, Roel
Storm, Gert
Ehling, Josef Ludger Anton
Kießling, Fabian
Lammers, Twan (Corresponding author)
[Journal Article]
Absolute MR thermometry using nanocarriers
In: Contrast media & molecular imaging, 9 (4), 283-290, 2014
[DOI: 10.1002/cmmi.1572]
Deckers, Roel
Sprinkhuizen, Sara M.
Crielaard, Bart J.
Ippel, Johannes H.
Boelens, Rolf
Bakker, Chris J. G.
Storm, Gert
Lammers, Twan
Bartels, Lambertus W.
[Journal Article]
Iron Oxide-Labeled Collagen Scaffolds for Non-Invasive MR Imaging in Tissue Engineering
In: Advanced functional materials, 24 (6), 754-762, 2014
[DOI: 10.1002/adfm.201301275]
Mertens, Marianne E.
Hermann, Alina
Bühren, Anne
Olde Damink, Leon
Möckel, Diana
Gremse, Felix
Ehling, Josef Ludger Anton
Kießling, Fabian
Lammers, Twan
[Journal Article]
PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses
In: Polymer chemistry, 5 (5), 1674-1681, 2014
[DOI: 10.1039/c3py01097j]
Ruiz-Hernandez, Eduardo
Hess, Michael
Melen, Gustavo J.
Theek, Benjamin
Talelli, Marina
Shi, Yang
Ozbakir, Burcin
Teunissen, Erik A.
Ramirez, Manuel
Möckel, Diana
Kießling, Fabian
Storm, Gert
Scheeren, Hans W.
Hennink, Wim E.
Szalay, Aladar A.
Strizker, Jochen
Lammers, Twan
[Journal Article]
Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines
In: Nano letters, 14 (2), 972-981, 2014
[DOI: 10.1021/nl404391r]
Kunjachan, Sijumon
Pola, Robert
Gremse, Felix
Theek, Benjamin
Ehling, Josef Ludger Anton
Möckel, Diana
Hermanns-Sachweh, Benita
Pechar, Michal
Ulbrich, Karel
Hennink, Wim E.
Storm, Gert
Lederle, Wiltrud
Kießling, Fabian
Lammers, Twan
[Journal Article]
Nanomedicines for Inflammatory Arthritis: Head-to-Head Comparison of Glucocorticoid-Containing Polymers, Micelles, and Liposomes
In: ACS nano, 8 (1), 458-466, 2014
[DOI: 10.1021/nn4048205]
Quan, Lingdong
Zhang, Yijia
Crielaard, Bart J.
Dusad, Anand
Lele, Subodh M.
Rijcken, Cristianne J. F.
Metselaar, Josbert M.
Kostková, Hana
Etrych, Tomas
Ulbrich, Karel
Kießling, Fabian
Mikuls, Ted R.
Hennink, Wim E.
Storm, Gert
Lammers, Twan (Corresponding author)
Wang, Dong (Corresponding author)
[Journal Article]
Micro-CT Imaging of Tumor Angiogenesis Quantitative Measures Describing Micromorphology and Vascularization
In: The American journal of pathology, 184 (2), 431-441, 2014
[DOI: 10.1016/j.ajpath.2013.10.014]
Ehling, Josef Ludger Anton
Theek, Benjamin
Gremse, Felix
Baetke, Sarah C.
Möckel, Diana
Maynard, Juliana
Ricketts, Sally-Ann
Grüll, Holger
Neeman, Michal
Knüchel-Clarke, Ruth
Lederle, Wiltrud
Kießling, Fabian
Lammers, Twan
[Journal Article]
Nondestructive monitoring of tissue-engineered constructs
In: Biomedizinische Technik = Biomedical engineering, 59 (2), 165-175, 2013, 2014
[DOI: 10.1515/bmt-2013-0029]
Frese, Julia
Morgenroth, Agnieszka
Mertens, Marianne E.
Koch, Sabine
Rongen, Lisanne
Vogg, Andreas
Zlatopolskiy, Boris D.
Neumaier, Bernd
Gesché, Valentine
Lammers, Twan
Schmitz-Rode, Thomas
Mela, Petra
Jockenhövel, Stefan
Mottaghy, Felix Manuel
Kießling, Fabian (Corresponding author)
[Journal Article]
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis
In: Gut : an international journal of gastroenterology and hepatology, 63 (12), 1960-1971, 2013
[DOI: 10.1136/gutjnl-2013-306294]
Ehling, Josef
Bartneck, Matthias
Wei, Xiao
Gremse, Felix
Fech, Viktor
Möckel, Diana
Baeck, Christer
Hittatiya, Kanishka
Eulberg, Dirk
Lüdde, Tom
Kießling, Fabian
Lammers, Twan (Corresponding author)
Tacke, Frank (Corresponding author)
[Contribution to a conference proceedings, Journal Article]
The liver-derived plasma protein histidine-rich glycoprotein promotes chronic liver injury and fibrosis by polarizing hepatic macrophages towards the inflammatory M1 phenotype
In: Hepatology : official journal of the American Association for the Study of Liver Diseases, 58 (Suppl. 1), 150, 283A-284A, 2013
Bartneck, Matthias
Fech, Viktor
Ehling, Josef Ludger Anton
Wei, Xiao
Warzecha, Klaudia Theresa
Hittatiya, Kanishka
Gaßler, Nikolaus
Lammers, Twan
Jahnen-Dechent, Wilhelm
Trautwein, Christian
Tacke, Frank
[Abstract, Contribution to a conference proceedings, Journal Article]
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis
In: Hepatology : official journal of the American Association for the Study of Liver Diseases, 58 (Suppl. 1), 205, 310A-310A, 2013
[DOI: 10.1002/hep.26825]
Bartneck, Matthias
Ehling, Josef Ludger Anton
Wei, Xiao
Fech, Viktor
Baeck, Christer
Hittatiya, Kanishka
Lüdde, Tom
Kießling, Fabian
Lammers, Twan
Trautwein, Christian
Tacke, Frank
[Contribution to a book, Journal Article]
Recent progress in nanomedicine: therapeutic, diagnostic and theranostic applications
In: Current opinion in biotechnology, 24 (6), 1159-1166, 2013
[DOI: 10.1016/j.copbio.2013.02.020]
Rizzo, Larissa Y.
Theek, Benjamin
Storm, Gert
Kießling, Fabian
Lammers, Twan
[Contribution to a book, Journal Article]
Multidrug resistance : Physiological principles and nanomedical solutions
In: Advanced drug delivery reviews, 65 (13/14), 1852-1865, 2013
[DOI: 10.1016/j.addr.2013.09.018]
Kunjachan, Sijumon
Rychlik, Blazej
Storm, Gert
Kießling, Fabian
Lammers, Twan
[Journal Article]
Rhodamine-Loaded Intercellular Adhesion Molecule-1-targeted Microbubbles for Dual-Modality Imaging Under Controlled Shear Stresses
In: Circulation / Cardiovascular imaging, 6 (6), 974-981, 2013
[DOI: 10.1161/CIRCIMAGING.113.000805]
Wu, Zhuojun
Curaj, Adelina
Fokong, Stanley
Liehn, Elisa Anamaria
Weber, Christian
Lammers, Twan
Kießling, Fabian
van Zandvoort, Marc A. M. J.
[Abstract, Contribution to a conference proceedings, Journal Article]
Pharmacological inhibition of ccl2 limits angiogenesis associated with chronic toxic liver injury in vivo by restraining infiltration of proangiogenic inflammatory monocytes
In: Journal of hepatology, 58 (S1), S451-S452, 2013
Bartneck, M.
Ehling, Josef Ludger Anton
Wei, X.
Fech, V.
Gaßler, Nikolaus
Eulberg, D.
Trautwein, Christian
Lammers, Twan
Tacke, Frank
[Journal Article]
Elastin-Based Molecular MRI of Liver Fibrosis
In: Hepatology : official journal of the American Association for the Study of Liver Diseases, 58 (4), 1517-1518, 2013
[DOI: 10.1002/hep.26326]
Ehling, Josef Ludger Anton
Bartneck, Matthias
Fech, Viktor
Butzbach, Britta
Cesati, Richard
Botnar, René M.
Lammers, Twan
Tacke, Frank
[Contribution to a book, Journal Article]
SMART drug delivery systems : Back to the future vs. clinical reality
In: International journal of pharmaceutics, 454 (1), 527-529, 2013
[DOI: 10.1016/j.ijpharm.2013.02.046]
Lammers, Twan
[Journal Article]
In vivo nanotoxicity testing using the zebrafish embryo assay
In: The journal of physical chemistry / B, Condensed matter, materials, surfaces, interfaces & biophysical chemistry, 1 (32), 3918-3925, 2013
[DOI: 10.1039/c3tb20528b]
Rizzo, Larissa Y.
Golombek, Susanne K.
Mertens, Marianne E.
Pan, Yu
Laaf, Dominic
Broda, Janine
Jayapaul, Jabadurai
Möckel, Diana
Subr, Vladimir
Hennink, Wim E.
Storm, Gert
Simon, Ulrich
Jahnen-Dechent, Wilhelm
Kießling, Fabian
Lammers, Twan
[Journal Article]
Comparison and systematic optimization of synthetic protocols for DOTA-hydrazide generation
In: Tetrahedron letters, 54 (8), 918-920, 2013
[DOI: 10.1016/j.tetlet.2012.11.151]
Fuge, Felix
Weiler, Marek
Gätjens, Jessica
Lammers, Twan
Kießling, Fabian
[Contribution to a conference proceedings, Journal Article]
Non-invasive imaging for studying anti-angiogenic therapy effects
In: Thrombosis and haemostasis, 109 (3), 375-390, 2013
[DOI: 10.1160/TH12-10-0721]
Ehling, Josef Ludger Anton
Lammers, Twan
Kießling, Fabian
[Journal Article]
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy
In: Biomaterials, 34 (4), 1255-1260, 2013
[DOI: 10.1016/j.biomaterials.2012.09.064]
Talelli, Marina
Oliveira, Sabrina
Rijcken, Cristianne J. F.
Pieters, Ebel H. E.
Etrych, Tomas
Ulbrich, Karel
van Nostrum, Rene C. F.
Storm, Gert
Hennink, Wim E.
Lammers, Twan
[Contribution to a conference proceedings, Journal Article]
Generation and imaging of patient customized implants
In: Biomedizinische Technik = Biomedical engineering, 57 (Suppl. 1), 2012
[DOI: 10.1515/bmt-2012-4388]
Frese, Julia
Schuster, Philipp
Mertens, M. E.
Vogg, Andreas
Dahlems, U.
Rongen, Lisanne
Koch, S.
Mela, Petra
Melmer, G.
Barth, Stefan
Mottaghy, Felix Manuel
Schmitz-Rode, Thomas
Lammers, Twan
Jockenhövel, Stefan
Kießling, Fabian
[Journal Article]
Non-invasive Imaging of Tissue-Engineered Vascular Endothelium with Iron Oxide Nanoparticles
In: Biomedizinische Technik = Biomedical engineering, 57 (Suppl. 1), 2012
[DOI: 10.1515/bmt-2012-4472]
Frese, Julia
Hrdlicka, L.
Mertens, M. E.
Rongen, Lisanne
Koch, Sabine
Schuster, Philipp
Gesché, Valentine
Lammers, Twan
Mela, Petra
Kießling, Fabian
Jockenhövel, Stefan
[Journal Article]
Personalized nanomedicine
In: Clinical cancer research, 18 (18), 4889-4894, 2012
[DOI: 10.1158/1078-0432.CCR-12-1414]
Lammers, Twan
Rizzo, Larissa Y.
Storm, Gert
Kießling, Fabian
[Journal Article]
Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors
In: Biomaterials, 33 (34), 8822-8829, 2012
[DOI: 10.1016/j.biomaterials.2012.08.036]
Jayapaul, Jabadurai
Arns, Susanne
Lederle, Wiltrud
Lammers, Twan
Comba, Peter
Gätjens, Jessica
Kießling, Fabian
[Journal Article]
Drug delivery research in Europe
In: Journal of controlled release, 161 (2), 151-151, 2012
[DOI: 10.1016/j.jconrel.2012.05.019]
Lammers, Twan
[Journal Article]
MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model
In: Journal of controlled release, 161 (3), 772-780, 2012
[DOI: 10.1016/j.jconrel.2012.05.004]
te Boekhorst, Bernard C.
Jensen, Linda B.
Colombo, Stefano
Varkouhi, Amir K.
Schiffelers, Raymond M.
Lammers, Twan
Storm, Gert
Nielsen, Hanne M.
Strijkers, Gustav J.
Foged, Gustav
Nicolay, Klaas
[Journal Article]
Nanomedicine on the move: from monotherapeutic regimens to combination therapies
In: Expert review of clinical pharmacology, 5 (2), 105-108, 2012
[DOI: 10.1586/ecp.12.3]
Lammers, Twan
[Journal Article]
Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis
In: Angewandte Chemie / International edition, 51 (29), 7254-7258, 2012
[DOI: 10.1002/anie.201202713]
Crielaard, Bart J.
Rijcken, Cristianne J.
Quan, Lingdong
van der Wal, Steffen
Altintas, Isil
van der Pot, Martin
Kruijtzer, John A.
Liskamp, Rob M.
Schiffelers, Raymond M.
van Nostrum, Cornelus F.
Hennink, Wim E.
Wang, Dong
Lammers, Twan
Storm, Gert
[Journal Article]
Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model
In: Alternatives to animal experimentation : ALTEX, 29 (3), 275-285, 2012
[DOI: 10.14573/altex.2012.3.275]
Leonard, Fransisca
Ali, Hussain
Collnot, Eva-Maria
Crielaard, Bart J.
Lammers, Twan
Storm, Gert
Lehr, Claus-Michael
[Journal Article]
Noninvasive Optical Imaging of Nanomedicine Biodistribution
In: ACS nano, 7 (1), 252-262, 2012, 2013
[DOI: 10.1021/nn303955n]
Kunjachan, Sijumon
Gremse, Felix
Theek, Benjamin
Koczera, Patrick
Pola, Robert
Pechar, Michal
Etrych, Tomas
Ulbrich, Karel
Storm, Gert
Kießling, Fabian
Lammers, Twan
[Contribution to a conference proceedings, Journal Article]
Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats
In: Journal of neurochemistry : JNC, 123 (Suppl. 2), 65-74, 2012
[DOI: 10.1111/j.1471-4159.2012.07945.x]
Tiebosch, Ivo A. C.
Crielaard, Bart J.
Bouts, Mark J. R. J.
Zwartbol, Rene
Salas-Perdomo, Angelica
Lammers, Twan
Planas, Anna M.
Storm, Gert
Dijkhuizen, Rick M.
[Journal Article]
Peptide-functionalized gold nanorods increase liver injury in hepatitis
In: ACS nano, 6 (10), 8767-8777, 2012
[DOI: 10.1021/nn302502u]
Bartneck, Matthias
Ritz, Thomas
Keul, Heidrun A.
Wambach, Mona
Bornemann, Jörg
Gbureck, Uwe
Ehling, Josef Ludger Anton
Lammers, Twan
Heymann, Felix
Gaßler, Nikolaus
Lüdde, Tom
Trautwein, Christian
Groll, Jürgen
Tacke, Frank
[Journal Article]
Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles
In: Journal of controlled release, 163 (1), 75-81, 2012
[DOI: 10.1016/j.jconrel.2012.05.007]
Fokong, Stanley
Theek, Benjamin
Wu, Zhuojun
Koczera, Patrick
Appold, Lia
Jorge, Samuel
Resch-Genger, Ute
van Zandvoort, Marc A. M. J.
Storm, Gert
Kießling, Fabian
Lammers, Twan
[Contribution to a conference proceedings, Journal Article]
Liposomes as carriers for colchicine-derived prodrugs : Vascular disrupting nanomedicines with tailorable drug release kinetics
In: European journal of pharmaceutical sciences, 45 (4), 429-435, 2012
[DOI: 10.1016/j.ejps.2011.08.027]
Crielaard, Bart J.
van der Wal, Steffen
Le, Huong Thu
Bode, Alois T. L.
Lammers, Twan
Hennink, Wim E.
Schiffelers, Raymond M.
Fens, Marcel H. A. M.
Storm, Gert
[Contribution to a conference proceedings, Journal Article]
Overcoming cellular multidrug resistance using classical nanomedicine formulations
In: European journal of pharmaceutical sciences, 45 (4), 421-428, 2012
[DOI: 10.1016/j.ejps.2011.08.028]
Kunjachan, Sijumon
Blauz, Andrzej
Möckel, Diana
Theek, Benjamin
Kießling, Fabian
Etrych, Tomas
Ulbrich, Karel
van Bloois, Louis
Storm, Gert
Bartosz, Grzegorz
Rychlik, Blazej
Lammers, Twan
[Journal Article]
Drug targeting systems for inflammatory disease : one for all, all for one
In: Journal of controlled release, 161 (2), 225-234, 2012
[DOI: 10.1016/j.jconrel.2011.12.014]
Crielaard, Bart J.
Lammers, Twan
Schiffelers, Raymond M.
Storm, Gert
[Journal Article]
Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
In: Journal of controlled release, 161 (2), 175-187, 2012
[DOI: 10.1016/j.jconrel.2011.09.063]
Lammers, Twan
Kießling, Fabian
Hennink, Wim E.
Storm, Gert
[Journal Article]
Theranostic systems and strategies for monitoring nanomedicine-mediated drug targeting
In: Current pharmaceutical biotechnology, 13 (4), 609-622, 2012
[DOI: 10.2174/138920112799436302]
Kunjachan, Sijumon
Jayapaul, Jabadurai
Mertens, Marianne E.
Storm, Gert
Kießling, Fabian
Lammers, Twan
[Journal Article]
Ultrasound microbubbles for molecular diagnosis, therapy, and theranostics
In: Journal of nuclear medicine : JNM, 53 (3), 345-348, 2012
[DOI: 10.2967/jnumed.111.099754]
Kießling, Fabian
Fokong, Stanley
Koczera, Patrick
Lederle, Wiltrud
Lammers, Twan
[Journal Article]
Fluorescent magnetoliposomes as a platform technology for functional and molecular mr and optical imaging
In: Contrast media & molecular imaging, 7 (1), 59-67, 2012
[DOI: 10.1002/cmmi.467]
Hodenius, Michael
Würth, Christian
Jayapaul, Jabadurai
Wong, John E.
Lammers, Twan
Gätjens, Jessica
Arns, Susanne
Mertens, Natascha
Slabu, Ioana
Ivanova, Gergana
Bornemann, Jörg
de Cuyper, Marcel
Resch-Genger, Ute
Kießling, Fabian
[Journal Article]
Physicochemical and biological aspects of macrophage-mediated drug targeting in anti-microbial therapy
In: Fundamental & clinical pharmacology : FCP, 26 (1), 63-71, 2012
[DOI: 10.1111/j.1472-8206.2011.00955.x]
Kunjachan, Sijumon
Jose, Sajan
Thomas, Cinu A.
Joseph, Emil
Kießling, Fabian
Lammers, Twan
[Journal Article]
Comparison of Polymeric siRNA Nanocarriers in a Murine LPS-Activated Macrophage Cell Line: Gene Silencing, Toxicity and Off-Target Gene Expression
In: Pharmaceutical research, 29 (3), 669-682, 2012
[DOI: 10.1007/s11095-011-0589-0]
Jensen, Linda B.
Griger, Joscha
Naeye, Broes
Varkouhi, Amir K.
Raemdonck, Koen
Schiffelers, Raymond M.
Lammers, Twan
Storm, Gert
de Smedt, Stefaan C.
Sproat, Brian S.
Nielsen, Hanne M.
Foged, Camilla
[Contribution to a conference proceedings, Journal Article]
MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate
In: European journal of pharmaceutical sciences, 45 (4), 436-441, 2012
[DOI: 10.1016/j.ejps.2011.08.022]
Cittadino, Evelina
Ferraretto, Marisa
Torres, Elena
Maiocchi, Alessandro
Crielaard, Bart J.
Lammers, Twan
Storm, Gert
Aime, Silvio
Terreno, Enzo
[Contribution to a conference proceedings, Journal Article]
Polyplexes based on cationic polymers with strong nucleic acid binding properties
In: European journal of pharmaceutical sciences, 45 (4), 459-466, 2012
[DOI: 10.1016/j.ejps.2011.09.002]
Varkouhi, Amir K.
Mountrichas, Grigoris
Schiffelers, Raymond M.
Lammers, Twan
Storm, Gert
Pispas, Stergios
Hennink, Wim E.
[Journal Article]
Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy
In: Theranostics, 1, 381-394, 2011
[DOI: 10.7150/thno/v01p0381]
Wiessler, Manfred
Hennrich, Ute
Pipkorn, Rüdiger
Waldeck, Waldemar
Cao, Liji
Peter, Jörg
Ehemann, Volker
Semmler, Wolfhard
Lammers, Twan
Braun, Klaus (Corresponding author)
[Journal Article]
A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy
In: International journal of nanomedicine, 6, 2697-2703, 2011
[DOI: 10.2147/IJN.S24450]
Crielaard, Bart J.
van der Wal, Steffen
Lammers, Twan
Le, Huong Thu
Hennink, Wim E.
Schiffelers, Raymond M.
Storm, Gert (Corresponding author)
Fens, Marcel H. A. M.
[Journal Article]
Macromolecular nanotheranostics for multimodal anticancer therapy
In: Nanoscale, 3 (10), 4022-4034, 2011
[DOI: 10.1039/c1nr10733j]
Huis in't Veld, Ruben
Storm, Gert
Hennink, Wim E.
Kießling, Fabian
Lammers, Twan
[Journal Article]
SiRNA delivery with functionalized carbon nanotubes
In: International journal of pharmaceutics, 416 (2 Special Issue: SI), 419-425, 2011
[DOI: 10.1016/j.ijpharm.2011.02.009]
Varkouhi, Amir Khashayar
Foillard, Stephanie
Lammers, Twan
Schiffelers, Raymond M.
Doris, Eric
Hennink, Wim E.
Storm, Gert
[Journal Article]
Double-Edged Role of the CXCL12/CXCR4 Axis in Experimental Myocardial Infarction
In: Journal of the American College of Cardiology : JACC, 58 (23), 2415-2423, 2011
[DOI: 10.1016/j.jacc.2011.08.033]
Liehn, Elisa Anamaria
Tuchscheerer, Nancy
Kanzler, Isabella
Drechsler, Maik
Fraemohs, Line Rebo
Schuh, Alexander Günter
Koenen, Robert Ryan
Zander, Simone
Söhnlein, Oliver
Hristov, Mihail
Grigorescu, Gabriela
Urs, Andreea O.
Leabu, Mircea
Bucur, Ilie
Merx, Marc Wilhelm
Zernecke, Alma
Ehling, Josef Ludger Anton
Gremse, Felix
Lammers, Twan
Kießling, Fabian
Bernhagen, Jürgen
Schober, Andreas
Weber, Christian
[Journal Article]
An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes
In: Journal of controlled release, 156 (3), 307-314, 2011
[DOI: 10.1016/j.jconrel.2011.07.023]
Crielaard, B. J.
Yousefi, A.
Schillemans, J. P.
Vermehren, C.
Buyens, K.
Braeckmans, K.
Lammers, T.
Storm, G.
[Journal Article]
Synthesis and Characterization of Biodegradable and Thermosensitive Polymeric Micelles with Covalently Bound Doxorubicin-Glucuronide Prodrug via Click Chemistry
In: Bioconjugate chemistry, 22 (12), 2519-2530, 2011
[DOI: 10.1021/bc2003499]
Talelli, M.
Morita, K.
Rijcken, C. J. F.
Aben, R. W. M.
Lammers, T.
Scheeren, H. W.
van Nostrum, C. F.
Storm, G.
Hennink, W. E.
[Journal Article]
Theranostic nanomedicine
In: Accounts of chemical research, 44 (10), 1029-1038, 2011
[DOI: 10.1021/ar200019c]
Lammers, Twan
Aime, Silvio
Hennink, Wim E.
Storm, Gert
Kießling, Fabian
[Contribution to a conference proceedings, Journal Article]
Macrophages and liposomes in inflammatory disease: friends or foes?
In: International journal of pharmaceutics, 416 (2), 499-506, 2011
[DOI: 10.1016/j.ijpharm.2010.12.045]
Crielaard, B. J.
Lammers, T.
Morgan, M. E.
Chaabane, L.
Carboni, S.
Greco, B.
Zaratin, P.
Kraneveld, A. D.
Storm, G.
[Journal Article]
Iron oxide nanoparticle-containing microbubble composites as contrast agents for MR and ultrasound dual-modality imaging
In: Biomaterials, 32 (26), 6155-6163, 2011
[DOI: 10.1016/j.biomaterials.2011.05.019]
Liu, Zhe
Lammers, Twan
Ehling, Josef Ludger Anton
Fokong, Stanley
Bornemann, Jörg
Kießling, Fabian
Gätjens, Jessica
[Journal Article]
Removable Nanocoatings for siRNA Polyplexes
In: Bioconjugate chemistry, 22 (2), 169-179, 2011
[DOI: 10.1021/bc100197e]
Kostka, Libor
Konak, Cestmir
Subr, Vladimir
Spirkova, Milena
Addadi, Yoseph
Neeman, Michal
Lammers, Twan
Ulbrich, Karel
[Contribution to a conference proceedings, Journal Article]
Gene silencing activity of siRNA polyplexes based on biodegradable polymers
In: European journal of pharmaceutics and biopharmaceutics, 77 (3), 2011
[DOI: 10.1016/j.ejpb.2010.11.016]
Varkouhi, Amir K.
Lammers, Twan
Schiffelers, Raymond M.
van Steenbergen, Mies J.
Hennink, Wim E.
Storm, Gert
[Journal Article]
Nanobody - Shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting
In: Journal of controlled release, 151 (2), 183-192, 2011
[DOI: 10.1016/j.jconrel.2011.01.015]
Talelli, Marina
Rijcken, Cristianne J. F.
Oliveira, Sabrina
van der Meel, Roy
van Bergen en Henegouwen, Paul M. P.
Lammers, Twan
van Nostrum, Cornelus F.
Storm, Gert
Hennink, Wim E.
[Contribution to a conference proceedings, Journal Article]
Reprint of 'Nanobody - Shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting'
In: Journal of controlled release, 153 (SI), 93-102, 2011
[DOI: 10.1016/j.jconrel.2011.06.003]
Talelli, Marina
Rijcken, Cristianne J. F.
Oliveira, Sabrina
van der Meel, Roy
van Bergen En Henegouwen, Paul M. P.
Lammers, Twan
van Nostrum, Cornelus F.
Storm, Gert
Hennink, Wim E.
[Journal Article]
FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells
In: Biomaterials, 32 (25), 5863-5871, 2011
[DOI: 10.1016/j.biomaterials.2011.04.056]
Jayapaul, Jabadurai
Hodenius, Michael
Arns, Susanne
Lederle, Wiltrud
Lammers, Twan
Comba, Peter
Kießling, Fabian
Gätjens, Jessica
[Journal Article]
Nanomedicine formulations for combination therapies
In: Nano reviews, 1, 2010
[DOI: 10.3402/nano.v1i0.5705]
Lammers, Twan
Storm, Gert
Kießling, Fabian
[Journal Article]
Long-Circulating and Passively Tumor-Targeted Polymer-Drug Conjugates Improve the Efficacy and Reduce the Toxicity of Radiochemotherapy
In: Advanced engineering materials, 12 (9), B413-B421, 2010
[DOI: 10.1002/adem.200980046]
Lammers, Twan
Subr, Vladimir
Ulbrich, Karel
Peschke, Peter
Huber, Peter E.
Hennink, Wim E.
Storm, Gert
Kießling, Fabian
[Journal Article]
Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy
In: Nano today, 5 (3), 197-212, 2010
[DOI: 10.1016/j.nantod.2010.05.001]
Lammers, Twan
Subr, Vladimir
Ulbrich, Karel
Hennink, Wim E.
Storm, Gert
Kießling, Fabian
[Journal Article]
Nanotheranostics and image-guided drug delivery: current concepts and future directions
In: Molecular pharmaceutics, 7 (6), 1899-1912, 2010
[DOI: 10.1021/mp100228v]
Lammers, Twan
Kießling, Fabian
Hennink, Wim E.
Storm, Gert
[Journal Article]
HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations
In: Nanomedicine, 5 (10), 1501-1523, 2010
[DOI: 10.2217/nnm.10.130]
Lammers, Twan
Subr, Vladimir
Ulbrich, Karel
Peschke, Peter
Huber, Peter E.
Hennink, Wim E.
Storm, Gert
Kießling, Fabian
[Journal Article]
Gene Silencing Activity of siRNA Polyplexes Based on Thiolated N,N,N-Trimethylated Chitosan
In: Bioconjugate chemistry, 21 (12), 2339-2346, 2010
[DOI: 10.1021/bc1003789]
Varkouhi, Amir K.
Verheul, Rolf J.
Schiffelers, Raymond M.
Lammers, Twan
Storm, Gert
Hennink, Wim E.
[Journal Article]
HPMA copolymers: 30 years of advances
In: Advanced drug delivery reviews, 62 (2), 119-121, 2010
[DOI: 10.1016/j.addr.2009.12.004]
Lammers, Twan
Ulbrich, Karel
[Journal Article]
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
In: Biomaterials, 31 (30), 7797-7804, 2010
[DOI: 10.1016/j.biomaterials.2010.07.005]
Talelli, Marina
Iman, Maryam
Varkouhi, Amir K.
Rijcken, Cristianne J. F.
Schiffelers, Raymond M.
Etrych, Tomas
Ulbrich, Karel
van Nostrum, Cornelus F.
Lammers, Twan
Storm, Gert
Hennink, Wim E.
[Journal Article]
Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations
In: Advanced drug delivery reviews, 62 (2), 203-230, 2010
[DOI: 10.1016/j.addr.2009.11.028]
Lammers, Twan
[Journal Article]
Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy
In: The British journal of cancer : BJC, 99 (6), 900-910, 2008
[DOI: 10.1038/sj.bjc.6604561]
Lammers, T.
Subr, V.
Peschke, P.
Kühnlein, R.
Hennink, W. E.
Ulbrich, K.
Kießling, Fabian
Heilmann, M.
Debus, J.
Huber, P. E.
Storm, G.