Alexandros Marios Sofias

Alexandros Marios Sofias Copyright: © Private
Lehrstuhl für Experimentelle Molekulare Bildgebung


Building: CBMS

Room: 109

Forckenbeckstraße 55

52074 Aachen


Phone: +49 241 80 85622

Dr. Alexandros Marios Sofias is a postdoctoral researcher at RWTH Aachen University (DE) and affiliated with the Norwegian University of Science and Technology (NTNU; NO). He holds a PhD in Nanomedicine (2019), a MSc in Pharmaceutical Sciences (2016), a Diploma in Pharmacy (2014), and he is a certified Radiation Protection Expert (2015) and Felasa C Researcher (2016). His research focuses on unraveling the intricate in vivo fate of cancer nanomedicine via multimodal and multiscale imaging (e.g., PET/CT imaging, and state-of-the-art Intravital Microscopy), and on the development of nanoimmunotherapeutics for targeting and manipulating the cancer-associated immune system, with particular focus on myeloid cells. He has previously conducted research in the field of nanomedicine, immunotherapy, and molecular imaging at the NTNU (NO), the Icahn School of Medicine at Mount Sinai (US), the Sanquin Institute (NL), the University of Toronto (CA), the Utrecht University (NL), and the University of Patras (GR). As part of ExMI, Alexandros has established or extended collaborations with Prof. Storm (Utrecht University, NL), Dr. Hak (Sintef Industry, NO), Prof. Koschmieder (RWTH Aachen University Hospital, DE), Prof. Lüdde (University Hospital Düsseldorf, DE), Dr. Matlung (Sanquin Institute, NL), and Cristal Therapeutics (NL).



Title Author(s)
Cyclic Arginine–Glycine–Aspartate‐Decorated Lipid Nanoparticle Targeting toward Inflammatory Lesions Involves Hitchhiking with Phagocytes
Journal Article (2021)
Sofias, Alexandros Marios (Corresponding author)
Bjørkøy, Geir
Ochando, Jordi
Sønstevold, Linda
Hegvik, Maria
Davies, Catharina de Lange
Haraldseth, Olav
Lammers, Twan
Mulder, Willem J. M.
Hak, Sjoerd (Corresponding author)
Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles
Contribution to a book, Journal Article (2020)
Biancacci, Ilaria
Sun, Qingxue
Möckel, Diana
Gremse, Felix
Rosenhain, Stefanie
Kiessling, Fabian
Bartneck, Matthias
Hu, Qizhi
Thewissen, Marielle
Storm, Gert
Hennink, Wim E.
Shi, Yang
Rijcken, Cristianne J. F.
Lammers, Twan
Sofias, Alexandros Marios
Dexamethasone nanomedicines for COVID-19
Journal Article (2020)
Lammers, Twan
Sofias, Alexandros Marios
van der Meel, Roy
Schiffelers, Raymond
Storm, Gert
Tacke, Frank
Koschmieder, Steffen
Brümmendorf, Tim H.
Kiessling, Fabian
Metselaar, Josbert M.
Cancer nanomedicine meets immunotherapy: opportunities and challenges
Journal Article (2020)
Sun, Qingxue
Bai, Xiangyang
Sofias, Alexandros Marios
van der Meel, Roy
Ruiz-Hernandez, Eduardo
Storm, Gert
Hennink, Wim E.
De Geest, Bruno G.
Kiessling, Fabian
Yu, Hai-Jun
Lammers, Twan (Corresponding author)
Shi, Yang (Corresponding author)